Nobel Prize Medicine winners announced

Nobel Prize awards to be announced starting October 2

A biological clock in the cells of plants, animals and humans anticipates these fluctuations to optimise behaviour and physiology.

"The paradigm-shifting discoveries by the laureates established key mechanisms for the biological clock", the Nobel Assembly said in its prize statement.

Hall and Rosbash, both then at Brandeis University in MA, and Young of Rockefeller University did research that found an elaborate internal clock of genes and the cellular functions that DNA controls working together in much the same way the gears and springs in an old-fashioned timepiece do, with interconnected functions controlling one another. Since 1978, he has been part of the faculty at Rockefeller University in New York City.

Michael Rosbash of Brandeis University, whose parents fled Nazi Germany and the son of a cantor, was one of three American scientists to win the Nobel Prize for Medicine.

The winners will share a prize of 9m Swedish kronor (£825,000), and each receive a medal engraved with their name. The pair highlighted how mutations in an unknown gene disrupted the circadian clock of flies, naming the gene "period".

Congress Let A Program That Insures 9 Million Kids Expire This Weekend
If Congress doesn't reauthorize the program, millions of children could eventually lose their current health insurance. Maryland, which has about 140,000 CHIP enrollees, has enough money to last through March, state officials estimate.

The next Nobels to be announced will be the Physics and Chemistry awards on Tuesday and Wednesday while the Literature award will be known on Thursday. A second clock gene, dubbed "timeless", encoded for a protein called TIM that binds to PER, and together they enter the cell nucleus.

In the fruit flies, a gene called period controlled the circadian rhythm, and when mutated, the insects lost the rhythms. Later, y identified more components of this internal clock, which also works on cells of or multicellular organisms, such as humans. Misalignments in this clock may result in medical conditions and disorders, as well as the temporary disorientation of jet lag that travelers experience when crisscrossing time zones.

Circadian rhythms help living organisms adapt their biological activities to the normal 24-hour cycle of light and darkness. Carlos Ibanez, another assembly member, said the research was important in understanding how humans adapt to shift work.

The trio won the prize for 'their discoveries of molecular mechanisms controlling the circadian rhythm'.

Related News:



Most liked

Second-year QBs Goff, Prescott meet
The Los Angeles Rams suffered the worst attendance drop in the National Football League since 1993, according to FiveThirtyEight . Todd Gurley scored the go-ahead touchdown on a 53-yard catch-and-run, and Greg Zuerlein kicked a career-high seven field goals.

Tigers' Andrew Romine to play all 9 positions vs Twins
You can see the fearlessness and the confidence he brings out there. "It made things fun", Romine told reporters. A few minutes later, Cain stood in the corner of the clubhouse with a smile on his face. "It made things light".

Israel Backing Kurdish Independence 'to Create New Conflicts, Destabilization'
Last Week, Iraq's Kurds announced a massive "yes" vote for independence following a referendum that has incensed Baghdad and sparked worldwide concern.